Ashley P. Tsang

Hello! I am a third-year Bioinformatics PhD Candidate in the Department of Computational Medicine and Bioinformatics at the University of Michigan. Previously, I studied at Johns Hopkins University, where I obtained a B.S. in Biomedical Engineering and Computer Science, and M.S.E in Biomedical Engineering.

My research interest lies at the intersection of AI and biology. Specifically, I’m passionate about developing AI-driven approaches to multi-modal data in order to characterize the tumor microenvironment and identify key drivers of cancer development and therapeutic response.

Please feel free to reach out if you’d like to chat further!

Selected Publications

Encoding functional edges in graphs to model spatially varying relationships in the tumor microenvironment
Ashley P Tsang(*), Santhoshi N Krishnan(*), Reva Kulkarni, Sagnik Bhadury, Marina Pasca di Magliano, Timothy L Frankel, Arvind Rao
Accepted to npj Artificial Intelligence, 2026
(*) indicates joint first authors

Assessing the tumor immune landscape across multiple spatial scales to differentiate immunotherapy response in metastatic non-small cell lung cancer
Ashley P Tsang(*), Santhoshi N Krishnan(*), Joel N Eliason(*), Jake J McGue, Angel Qin, Timothy L Frankel, Arvind Rao
Laboratory Investigation, 2024
[Journal]
(*) indicates joint first authors

Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R, and GenePattern Notebook implementations of CoGAPS
Jeanette A I Johnson(*), Ashley P Tsang(*), Jacob T Mitchell, Emily F Davis-Marcisak, Thomas Sherman, Ted Liefeld, Melanie Loth, Loyal Goff, Jacquelyn Zimmerman, Ben Kinny-Köster, Elizabeth Jaffee, Pablo Tamayo, Jill Mesirov, Michael Reich, Elana J Fertig, Genevieve L Stein-O’Brien
Nature Protocols, 2023
[Journal][Code]
(*) indicates joint first authors